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UF Health University of Florida
Dr. Zhoumeng Lin's Lab College of Public Health and Health Professions
Qiran Chen

Qiran Chen, PHD

Postdoctoral Fellow

Department: Department of Environmental and Global Health
Business Phone: (352) 273-9188
Business Email: chenqiran@ufl.edu
CV: View Curriculum Vitae

About Qiran Chen

Dr. Qiran Chen received her B.S. degree in Biological Science from Nankai University in 2012, a M.P.H. in Epidemiology from Indiana University in 2014 and a Ph.D. in Environmental Health from Indiana University Bloomington in 2020 (mentor James E Klaunig and Kan Shao). Before joining the University of Florida, Dr. Chen was a postdoctoral fellow at the Institute of Computational Comparative Medicine at Kansas State University.

Dr. Chen’s research has focused on the human risk assessment of environmental chemicals and nanoparticles using the advanced computational methodologies. Her studies have received several awards, including the Andersen-Clewell Trainee Award of the Risk Assessment Specialty Section, and the Dharm V. Singh Carcinogenesis Graduate Student Award of the Carcinogenesis Specialty Section in the Society of Toxicology in 2020.

Accomplishments

Dharm V. Singh Carcinogenesis Graduate Student Award of the Year 2020
2020 · Carcinogenesis Specialty Section, Society of Toxicology
Andersen-Clewell Trainee Award of the Year 2020
2019 · Risk Assessment Specialty Section, Society of Toxicology
Student Merit Award
2017 · Dose-Response Specialty Group, Society of Risk Analysis

Research Profile

Dr. Chen’s research has focused on the risk assessment of environmental chemicals and nanoparticles with advanced computational methodologies. The computational methodologies include physiologically based pharmacokinetic (PBPK) modeling, toxicogenomics, machine learning, and artificial intelligence (AI).

Open Researcher and Contributor ID (ORCID)

0000-0002-0883-9789

Publications

Academic Articles
2024
Development of a Physiologically Based Pharmacokinetic Model for Flunixin in Cattle and Swine Following Dermal Exposure.
Toxicological sciences : an official journal of the Society of Toxicology. [DOI] 10.1093/toxsci/kfae139. [PMID] 39475069.
PubMed · Publisher’s Site
2024
Predicting tissue distribution and tumor delivery of nanoparticles in mice using machine learning models.
Journal of controlled release : official journal of the Controlled Release Society. 374:219-229 [DOI] 10.1016/j.jconrel.2024.08.015. [PMID] 39146980.
PubMed · Publisher’s Site
2024
Residue depletion profiles and withdrawal intervals of florfenicol and its metabolite florfenicol amine in plasma and milk of lactating goats after repeated subcutaneous administrations.
Regulatory toxicology and pharmacology : RTP. 153 [DOI] 10.1016/j.yrtph.2024.105707. [PMID] 39304113.
PubMed · Publisher’s Site
2023
An artificial intelligence-assisted physiologically-based pharmacokinetic model to predict nanoparticle delivery to tumors in mice.
Journal of controlled release : official journal of the Controlled Release Society. 361:53-63 [DOI] 10.1016/j.jconrel.2023.07.040. [PMID] 37499908.
8 citations · PubMed · Publisher’s Site
2023
Meta-Analysis of Nanoparticle Distribution in Tumors and Major Organs in Tumor-Bearing Mice.
ACS nano. 17(20):19810-19831 [DOI] 10.1021/acsnano.3c04037. [PMID] 37812732.
3 citations · PubMed · Publisher’s Site
2023
Pharmacokinetics and tumor delivery of nanoparticles.
Journal of drug delivery science and technology. 83 [DOI] 10.1016/j.jddst.2023.104404. [PMID] 38037664.
PubMed · Publisher’s Site
2023
Pharmacokinetics, tissue residue depletion, and withdrawal interval estimations of florfenicol in goats following repeated subcutaneous administrations.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 181 [DOI] 10.1016/j.fct.2023.114098. [PMID] 37838212.
PubMed · Publisher’s Site
2023
Quantitative Integration of Mode of Action Information in Dose-Response Modeling and POD Estimation for Nonmutagenic Carcinogens: A Case Study of TCDD.
Environmental health perspectives. 131(12) [DOI] 10.1289/EHP12677. [PMID] 38157272.
1 citation · PubMed · Publisher’s Site
2022
Integration of Toxicogenomics and Physiologically Based Pharmacokinetic Modeling in Human Health Risk Assessment of Perfluorooctane Sulfonate.
Environmental science & technology. 56(6):3623-3633 [DOI] 10.1021/acs.est.1c06479. [PMID] 35194992.
16 citations · PubMed · Publisher’s Site
2022
Toxicokinetics, dose-response, and risk assessment of nanomaterials: Methodology, challenges, and future perspectives.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 14(6) [DOI] 10.1002/wnan.1808. [PMID] 36416026.
PubMed · Publisher’s Site
2019
Quantifying association between liver tumor incidence and early-stage liver weight increase – An NTP data analysis.
Toxicology reports. 6:674-682 [DOI] 10.1016/j.toxrep.2019.07.001. [PMID] 31360640.
1 citation · PubMed · Publisher’s Site
2018
Association of herbal/botanic supplement use with quality of life, recurrence, and survival in newly diagnosed stage II colon cancer patients: A 2-y follow-up study.
Nutrition (Burbank, Los Angeles County, Calif.). 54:1-6 [DOI] 10.1016/j.nut.2018.02.002. [PMID] 29674230.
1 citation · PubMed · Publisher’s Site

Education

Doctor of Philosophy in Environmental Health
2020 · Indiana University Bloomington
Master of Public Health in Epidemiology
2014 · Indiana University Bloomington
Bachelor of Science in Biological Science
2012 · Nankai University, China

Contact Details

Phones:
Business:
(352) 273-9188
Emails:
Business:
chenqiran@ufl.edu
Addresses:
Business Mailing:
PO Box 100188
 GAINESVILLE FL 32610