Dr. Chou gives a guest lecture entitled “An introduction to computational modeling and artificial intelligence in exposure science and its application in environmental chemicals, animal drugs, and nanomedicine” for the course “PHC 6702: Environmental Monitoring and Exposure Assessment” at UF. (04/05/2023)
Long’s and Qiran’s review article entitled “Pharmacokinetics and tumor delivery of nanoparticles” has been accepted by the Journal of Drug Delivery Science and Technology. Congratulations! (03/30/2023)
The Lin lab members did three presentations in the Lake Nona Leadership Council Meeting at the UF Research and Academic Center – Lake Nona on March 28, 2023. Ms. Xue Wu did an “shark tank” style platform presentation entitled “Predicting Withdrawal Times of Flunixin in Cattle Following Dermal Exposure Using a PBPK Model”. Dr. Qiran Chen did a poster presentation entitled “Pharmacostatistical analysis of tissue distribution of nanoparticles in tumor-bearing mice”. Dr. Malek Hussein Hajjawi did a poster presentation entitled “Development of a Population Pharmacokinetic Model for Oxytetracycline in Sheep Using a Nonlinear Mixed Effects Approach”. (03/28/2023)
Our lab was recognized for leadership, presented several poster and platform presentations, and received several awards at the Society of Toxicology 62nd Annual Meeting held March 19-23 in Nashville. Congratulations to the entire team for another great year! Our lab’s accomplishments have been featured at the college’s website here. The services and awards are listed here. (03/23/2022)
Members of the Lin Lab provided the following services:
Zhoumeng Lin served as the Chair of the Poster Session on “Computational Toxicology I”. Lin completed his two-year service as the Council for the Nanoscience and Advanced Materials Specialty Section and received the “Outstanding Service as a Councilor Award”. Lin is now in his second year in the Presidential Chain of the Biological Modeling Specialty Section and will start his third year service as the President starting May 1, 2023.
Wei-Chun Chou was elected as a Councilor of the Biological Modeling Specialty Section.
Qiran Chen served as Chair of the Poster Session on “Computational Toxicology II”. Chen was elected as the Postdoctoral Representative of the Biological Modeling Specialty Section.
Members of the Lin Lab received the following awards:
Best Publication Award of the Year 2022 presented by Nanoscience and Advanced Materials Specialty Section; Recipients: Wei-Chun Chou and Zhoumeng Lin; Title of the publication “Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats”. Link to the publication: https://doi.org/10.1186/s12989-022-00489-4
Outstanding Postdoctoral Award presented by Nanoscience and Advanced Materials Specialty Section; Recipient: Qiran Chen
Best Postdoctoral Publication Award presented by Society of Toxicology; Recipient: Qiran Chen
Perry J. Gehring Biological Modeling Endowment Award presented by Biological Modeling Specialty Section; Recipient: Xue Wu
Best Trainee Abstract Award Honorable Mention presented by Biological Modeling Specialty Section; Recipient: Xue Wu; Title of Xue’s abstract “Development of a Physiologically Based Pharmacokinetic (PBPK) Model for Flunixin in Cattle and Swine Following Dermal Exposure”
Dr. Lin gives a guest lecture entitled “Integrating Physiologically Based Pharmacokinetic (PBPK) Modeling with Artificial Intelligence (AI) to Predict Nanoparticle Delivery to Tumors” to students in Department of Pharmaceutical Sciences at St. John’s University. (03/16/2023)
Dr. Lin gives a guest lecture entitled “Xenobiotic transport in the body – Physiologically based pharmacokinetic (PBPK) modeling” to the course of “VME 6934: Ecotoxicology and Risk Assessment” at UF. (01/18/2023)
Pei-Yu joins our lab as a PhD student in Public Health with a Concentration in Environmental Health. Welcome! (01/03/2023)
Dr. Lin gives a presentation entitled “An interactive generic physiologically based pharmacokinetic modeling platform to predict meat and milk residues and withdrawal intervals for perfluorooctanoic acid, perfluorooctane sulfonate and perfluorohexane sulfonate in beef and dairy cattle” at the Annual Meeting of Society for Risk Analysis (SRA) in Tampa. (12/06/2022)
Our collaborative manuscript entitled “Integration of In Vitro and In Vivo Models to Predict Cellular and Tissue Dosimetry of Nanomaterials Using Physiologically Based Pharmacokinetic Modeling” has been accepted by ACS Nano. This is great news! Congratulations to the entire team! (12/02/2022)
Dr. Jia-Sheng Wang from the University of Georgia visits UF and gives a seminar in our department. Dr. Wang also joins our lab meeting and provides comments on our projects. Thank you! (11/16/2022)
Malek joins our lab as a Postdoctoral Fellow. Welcome! (10/28/2022)
Lin is now certified as European Registered Toxicologist (ERT) through UK Register of Toxicologists. Good news! (11/15/2022)
FARAD celebrates its 40th anniversary in Austin. Congratulations to the entire team! (11/08/2022)
Wei-Chun’s manuscript entitled “Machine learning and artificial intelligence in physiologically based pharmacokinetic modeling” has been accepted by Toxicological Sciences. Congratulations! (09/22/2022)
Xue joins our lab as a PhD student in Public Health with a Concentration in Environmental Health. Welcome! (08/22/2022)
Long’s last day with UF. Congratulations again to Long! (08/21/2022)
Long is about to complete his two-year postdoc training and has accepted a new position as Senior Scientist in Pharmacometrics in Neurocrine Biosciences, Inc. in San Diego, CA. In the last two years, Long received training in various pharmacometrics methods, including traditional PK and PBPK modeling. Long has published two first-authored papers, and has a couple of more papers that are in preparation. Long has also received several national and regional awards, including the Andersen-Clewell Trainee Award presented jointly by the Risk Assessment Specialty Section and Biological Modeling Specialty Section of Society of Toxicology in 2022 and the John Doull Risk Assessment Award presented by Risk Assessment Specialty Section of Society of Toxicology in 2021. Congratulations to Long and thanks to his contributions to the lab! (08/05/2022)
The UF Component of the Food Animal Residue Avoidance Databank (FARAD) Program has received the 2022 Award. Congratulations to the entire FARAD team! (08/04/2022)
Long’s manuscript entitled “A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in broiler chickens and laying hens” has been accepted by Food and Chemical Toxicology. Congratulations to the entire collaborative team! (07/25/2022)
Our lab’s article entitled “Machine learning and artificial intelligence in toxicological sciences” has been accepted for publication in Toxicological Sciences. Great news! (07/02/2022)
Wei-Chun’s manuscript entitled “Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats” has been accepted by Particle and Fibre Toxicology. Congratulations! (06/28/2022)
Our lab’s Nano AI PBPK work is featured in the main page of our department website here. Congratulation to the entire lab! (06/07/2022)
Zhoumeng and Wei-Chun present our work for a webinar hosted jointly by National Health Research Institutes and National Yang Ming Chiao Tung University of Taiwan. The title of Zhoumeng’s talk is “Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling in Nanomedicine and Food Safety Assessment and Roles of Artificial Intelligence (AI) Approaches in these Areas”. The title of Wei-Chun’s talk is “Development of Physiologically Based Pharmacokinetic (PBPK) Models Within Bayesian Framework and roles of artificial intelligence technologies in human health risk assessment: a case study with perfluorooctane sulfonate (PFOS)”. (05/18/2022)
Wei-Chun’s paper entitled “An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol and Penicillin G” has been accepted by Toxicological Sciences. Congratulations! (05/20/2022)
Long’s paper entitled “Residue depletion profiles and withdrawal interval estimations of meloxicam in eggs and ovarian follicles following intravenous (Meloxicam Solution for Injection) and oral (Meloxidyl®) administration in domestic chickens (Gallus domesticus)” has been accepted by Regulatory Toxicology and Pharmacology. Congratulations! (04/15/2022)
Qiran’s paper entitled “Toxicokinetics, dose-response and risk assessment of nanomaterials: methodology, challenges, and future perspectives” has been accepted by WIREs Nanomedicine & Nanobiotechnology. Congratulations! (04/12/2022)
Gabriel’s paper entitled “Development of a physiologically based pharmacokinetic model to predict irinotecan disposition during inflammation” has been accepted by Chemico-Biological Interactions. Congratulations! (04/11/2022)
As usual, our lab presents multiple posters and platform presentations and receive several awards at the Annual Meeting of Society of Toxicology. Congratulations to the entire team for another great year! Our lab’s accomplishments have been featured at the college’s website here. The awards are listed here. Please refer to the SOT Program for details of our presentations. (03/22/2022)
JOINN Biomere Outstanding Young Toxicologist Award presented by the American Association of Chinese in Toxicology Special Interest Group Recipient: Zhoumeng Lin
Perry J. Gehring Biological Modeling Endowment Award presented by the Biological Modeling Specialty Section Recipient: Qiran Chen, Ph.D., postdoctoral fellow
Andersen-Clewell Trainee Award presented jointly by the Risk Assessment Specialty Section and Biological Modeling Specialty Section Recipient: Long Yuan, Ph.D., postdoctoral fellow
Andersen-Clewell Trainee Award (Honorable Mention) presented jointly by the Risk Assessment Specialty Section and Biological Modeling Specialty Section Recipient: Qiran Chen
Best Trainee Abstract Award (Honorable Mentions) presented by the Biological Modeling Specialty Section Recipients: Qiran Chen and Long Yuan
Ning’s manuscript entitled “Comparative pharmacokinetics of sulfadiazine and its metabolite N4-acetyl sulfadiazine in grass carp (Ctenopharyngodon idella) at different temperatures after oral administration” has been accepted by Pharmaceutics. Congratulations! (03/22/2020)
Congratulations to Gabriel on his new position as a Senior Scientist in the ADME & Discovery Group at Merch in Boston, MA. Gabriel will start this new position in March. We are very proud of you. (02/25/2022)
Qiran’s manuscript entitled “Integration of Toxicogenomics and Physiologically Based Pharmacokinetic (PBPK) Modeling in Human Health Risk Assessment of Perfluorooctane Sulfonate (PFOS)” has been accepted by Environmental Science & Technology. Congratulations! (02/11/2022)
Qiran, Wei-Chun, and Long receive the Postdoctoral Fellow Poster Awards of the 2021 Annual Meeting of Southeastern Society of Toxicology (SESOT). Congratulations to all! (12/20/2021)
Qiran’s poster title is “The Implementation of Toxiocogenomics and Physiologically Based Pharmacokinetic (PBPK) modeling to the Human Health Risk Assessment of Perfluorooctane Sulfonate (PFOS)”.
Wei-Chun’s poster title is “A web-based platform based on a generic physiologically based pharmacokinetic (PBPK) model to predict withdrawal intervals of flunixin, florfenicol, and penicillin G in cattle and swine”.
Long’s poster title is “A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in domestic chickens”.
Dr. Lin delivers a webinar entitled “Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling in Nanomedicine, Food Safety and Human Health Risk Assessment and Roles of Artificial Intelligence (AI) Approaches in these Areas”. This is part of the webinar series hosted by ScitoVation, Durham, NC. The recording is available here. (12/07/2021)
Dr. Lin is named in the World’s Top 2% Scientists List in 2020 published by Stanford University. Here is the full citation information of this list. “Baas, Jeroen; Boyack, Kevin; Ioannidis, John P.A. (2021), “August 2021 data-update for “Updated science-wide author databases of standardized citation indicators””, Mendeley Data, V3, doi: 10.17632/btchxktzyw.3”. (11/22/2021)
Riad’s last day with UF. Congratulations again to Riad! (10/29/2021)
Our lab receives a new subcontract from The Children’s Hospital of Philadelphia (CHOP). The objective of this subcontract is to identify efficient sampling interval to effectively construct time-concentration profile of bisphenol A in the infant’s urine using a PBPK model. This new subcontract becomes part of the existing subcontract between CHOP and UF that is led by the PI Dr. Eric Coker. Dr. Lin is Co-PI of this subcontract. (10/06/2021)
Our lab’s R01 grant is featured on PHHP website. Check it out here. This news has also been picked up by Nano Magazine and NanoWerk. (09/30/2021).
Dr. Lin gives a seminar entitled “Application of Pharmacometrics in Veterinary Medicine and Translation of Pharmacokinetics/Pharmacodynamics from Animals to Humans” as part of the EGH seminar series. A recorded presentation is available upon request. (09/30/2021)
Riad has accepted a new position as Senior Quantitative Systems Pharmacologist 1 in AbbVie in North Chicago, IL. Riad completed his postdoc training within only a little bit more than one year. During this time, he received the Andersen-Clewell Trainee Award of Biological Modeling Specialty Section and Risk Assessment Specialty Section of Society of Toxicology, and he published one manuscript in Toxicological Sciences. He also completed the manuscript draft of his second major project and had great progress on his third project. Congratulations to Riad and thanks to his contributions to the lab! (09/27/2021)
Our lab receives a new subaward to develop a PBPK model for PFOS in daily cows from University of California-Davis. (09/10/2021)
Our lab receives our first R01 grant from NIH. This grant is based on extensive foundational work from our lab in the last several years. Thanks to the contributions from prior and current lab members and collaborators. Congratulations to all! (09/01/2021)
Gabriel has completed his training at UF and returned back to his home university. This summer, Gabriel learned PBPK modeling and developed a PBPK model for irinotecan in mice and humans as part of his PhD dissertation. (08/22/2021)
Dr. Lin has completed the UF First Year Faculty Teaching Academy (FYFTA) program. This is part of the preparation to develop and teach new courses at UF beginning in 2022. (08/04/2021)
Riad’s manuscript entitled “Development and Application of an interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats” has been accepted by Toxicological Sciences. Congratulations! (07/27/2021)
The UF Component of the Food Animal Residue Avoidance Databank (FARAD) Program has received the 2021 Award. Congratulations to the entire FARAD team! (07/20/2021)
Gabriel has joined our lab as a Visiting PhD Student. Welcome! (07/12/2021)
Dr. Lin and all his lab members have moved to the University of Florida. (05/28/2021)
