News

  • Our lab’s 2024 photos. (12/06/2024)2024 Lab
  • Jared Brown from University of Colorado Anschutz Medical Campus visited us and gave an EGH seminar entitled “Unveiling the Hidden Dangers: The Role of Sugarcane Burning and Silica Nanoparticles in Chronic Kidney Disease of Unknown Etiology”. Thank you! (11/20/2024)2024-11 Dr. Brown
  • Donna Zhang from The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology visited us and gave an EGH seminar entitled “NRF2 in Environmental Response and Disease Intervention”. Thank you! (11/13/2024)2024 Dr. Zhang
  • Our lab’s research is highlighted in the UF PHHP Researcher Spotlight Series. Check out the video here. Thanks to the PHHP Communications Office and Instructional Design and Education Technology Office for helping create this video. (11/12/2024)
  • Pei-Yu did a poster presentation entitled “Artificial Intelligence and Machine Learning-Assisted Multi-Task Quantitative Structure-Activity Relationship Model for Predicting Human Multi-Organ Toxicity” and Chi-Yun did a poster presentation entitled “’QSAR classification models for predicting chemical carcinogenicity at organ system level via machine learning and deep learning algorithms’” in the 2024 UF AI Days. Great job! (10/29/2024)2024 UF AI
  • Dr. Lin gave an invited presentation entitled “Applications of machine learning and AI approaches to develop PBPK and QSAR models to predict ADMET properties to aid chemical safety assessment” at the workshop entitled “Integrating AI into chemical safety assessment: opportunities, challenges, and the path forward” organized by the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) in Sophia Antipolis, France. (10/17/2024)2024 France
  • Xue’s second manuscript as the first author entitled “Development of a Physiologically Based Pharmacokinetic Model for Flunixin in Cattle and Swine Following Dermal Exposure” has been accepted by Toxicological Sciences. Congratulations! (10/14/2024)
  • Chi-Yun’s manuscript entitled “A physiologically based toxicokinetic model for microplastics and nanoplastics in mice after oral exposure and its implications for human dietary exposure assessment” has been accepted by the Journal of Hazardous Materials. Congratulations! (09/19/2024)
  • Pei-Yu’s first PhD paper entitled “Development of Machine Learning-Based Quantitative Structure-Activity Relationship Models for Predicting Plasma Half-Lives of Drugs in Six Common Food Animal Species” has been accepted by Toxicological Sciences. Congratulations! (09/17/2024)
  • Dr. Lin is named in the World’s Top 2% Scientists List 2024 by Stanford University. Dr. Lin has been continuously named in the World’s Top 2% Scientists Lists from 2021 to 2024. Check it out here. (09/16/2024)
  • Qiran’s paper entitled “Residue Depletion Profiles and Withdrawal Intervals of Florfenicol and its Metabolite Florfenicol Amine in Plasma and Milk of Lactating Goats after Repeated Subcutaneous Administrations” has been accepted by Regulatory Toxicology and Pharmacology. Congratulations! (09/16/2024)
  • Kun did a poster presentation entitled “A machine learning-based quantitative structure-activity relationship model to predict tissue distribution and tumor delivery of nanoparticles in mice” and Dr. Lin did a platform presentation entitled “Predicting tissue distribution and tumor delivery of nanoparticles using machine learning and artificial intelligence approaches” in the 22nd International Nanomedicine and Drug Delivery Symposium (NanoDDS). (09/15/2024)Kun NanoDDS
  • Our lab (Wei-Chun, Qiran, and Zhoumeng) contributes to a new manuscript entitled “Physiologically Based Pharmacokinetic Modeling of Metal Nanoparticles: A State-of-the-Science Expert Panel Review” that has been accepted by Nanotoxicology. (08/29/2024)
  • Xinyue joins our lab as a PhD student. Welcome! (08/16/2024)
  • Kun’s manuscript entitled “Predicting tissue distribution and tumor delivery of nanoparticles in mice using machine learning models” has been accepted for publication in Journal of Controlled Release. (08/11/2024)
  • Dr. Lin was named a Top Scholar by ScholarGPS. Dr. Lin was ranked in the top 0.5% of scholars in the specialty of Pharmacokinetics based on the publication record, the impact and the quality of scholarly contributions in the last 5 years. Check it out here for more details. (07/31/2024)
  • Pei-Yu received the 2024-2025 PHHP PhD Fellowship in Artificial Intelligence (AI). Congratulations! (07/09/2024)
  • Chi-Yun’s manuscript entitled “Exploring the potential and challenges of developing physiologically-based toxicokinetic models to support human health risk assessment of microplastic and nanoplastic particles” has been accepted by Environment International. Congratulations! (03/28/2024)
  • Dr. Natalia V. de Moraes from UF CPSP and Dr. Anderson de Oliveira from University of Sao Paulo, Brazil visited our lab today. We had a great time sharing research projects and discussing potential collaborative projects. (03/22/2024)

    Dr Natalia de Moraes

  • Our lab was recognized for leadership, presented several poster and platform presentations, and received several awards at the Society of Toxicology 63rd Annual Meeting held March 10-14 in Salt Lake City. Congratulations to the entire team for another great year! Our lab’s accomplishments have been featured at the college’s website here. The services and awards are listed here. (03/14/2024)

    2024-03-14 SOT

     
    • Members of the Lin Lab provided the following services:
      • Zhoumeng Lin served as a Co-Chair of a Workshop Session on “Use of PBPK and Novel Pharmacokinetic Approaches for the Quantitative Prediction of Tissue Residue and Withdrawal Times for Human Food Safety Assessment”. Zhoumeng is now in his third year in the Presidential Chain of the Biological Modeling Specialty Section and is serving as the President for the current term from May 2023 to April 2024.
      • Chi-Yun Chen was elected as the Postdoctoral Representative of the Risk Assessment Specialty Section of Society of Toxicology.
      • Qiran Chen was elected as the Postdoctoral Representative of the American Association of Chinese in Toxicology (AACT) Specialty Interest Group of Society of Toxicology.
      • Xue was elected as the Graduate Student Representative of the Biological Modeling Specialty Section of Society of Toxicology.
    • Members of the Lin Lab received the following awards:
      • Best Paper Award of the Year 2023 presented by Biological Modeling Specialty Section; Lead author: Wei-Chun Chou; Corresponding author: Zhoumeng Lin; Title of the paper “An artificial intelligence-assisted physiologically-based pharmacokinetic model to predict nanoparticle delivery to tumors in mice”. Link to the publication: https://pubmed.ncbi.nlm.nih.gov/37499908/.
      • Perry J. Gehring Biological Modeling Endowment Award presented by Biological Modeling Specialty Section; Recipient: Chi-Yun Chen.
      • AACT and InnoStar Best Abstract Award (2nd Place) presented by AACT Specialty Interest Group; Recipient: Qiran Chen; Title of Qiran’s presentation: “A physiologically based pharmacokinetic model of perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), and perfluorodecanoic acid (PFDA) in adult zebrafish”.
      • Top 10 Best Abstract Award presented by Risk Assessment Specialty Section; Recipient: Chi-Yun Chen; Title of Chi-Yun’s presentation: “A physiologically based toxicokinetic model for assessing oral exposure to microplastics and nanoplastics in mice and its implications for human dietary intake”.
      • Top 10 Best Abstract Awards presented by Computational Toxicology Specialty Section; Recipients: Chi-Yun Chen, Qiran Chen, Pei-Yu Wu; Title of Pei-Yu’s presentation: “A Physiologically-Based Pharmacokinetic (PBPK) Model of Perfluorobutane Sulfonate (PFBS) in Rodents with a Bayesian Approach”.
      • Best Trainee Abstract Award Honorable Mentions presented by Biological Modeling Specialty Section; Recipients: Chi-Yun Chen, Qiran Chen, Pei-Yu Wu, Xue Wu, Zhicheng Zhang; Title of Xue’s presentation: “Predicting the Plasma Half-Life of Medications Administered to Dogs: An Artificial Intelligence Based Quantitative Structure-Activity Relationship (AI-QSAR) Model”; Title of Zhicheng’s presentation: “Comparison of PK-Sim® and R Statistical Computing and Graphics System for Physiologically Based Pharmacokinetic Model Development for Meloxicam in Broiler Chickens and Laying Hens”
    • In addition, Kun did a poster presentation entitled: “Applying machine learning and artificial intelligence approaches to predict tissue distribution and tumor delivery of nanoparticles in mice following intravenous injection”. Wei-Chun also did a poster presentation entitled “Development of a Multi-Organ Toxicity Predictive Model Using Multi-Task Learning in Deep Neural Network”. Xue did a platform presentation entitled “Predicting the Plasma Half-Life of Medications Administered to Dogs: An Artificial Intelligence Based Quantitative Structure-Activity Relationship (AI-QSAR) Model” for the “Machine Learning in Toxicology” platform session. Zhoumeng gave a platform presentation entitled “Development and applications of PBPK models to predict tissue residues and withdrawal times of drugs in food-producing animals to support food safety assessment”.

  • Dr. Cecilia (Yu-Mei) Tan from US EPA gave a seminar to our department and visited our lab. Dr. Tan also provided career development advice to many of our lab members. Thank you! (01/17/2024)

    Dr. Cecilia Tan

  • The Lin Lab End-of-Year Celebration at the UF Gator Corner Dining Center. This year we have a lot to celebrate. Wei-Chun found a tenure-track faculty position and published several manuscripts and submitted two NIH proposals as PI this year. Malek found a new position as Clinical Pharmacology Fellow in which he can do his interested work in PBPK modeling for drugs in humans with clinical implications. Qiran published her ACS Nano paper and submitted her K99/R00 proposal and received several awards. Xue published her first first-authored manuscript and received the PHHP PhD Fellowship in AI. Pei-Yu completed her first project and is writing a manuscript. Chi-Yun completed her first manuscript draft and had significant progress on her second project. Zhicheng also had significant progress on his first two projects. Nithin and Yashas deployed the Nano-Tumor Database. Congratulations to everyone and keep up the great work! (12/31/2023)

    2023 Lab Photo

  • Wei-Chun has accepted a tenure-track Assistant Professor position in Department of Environmental Sciences at University of California, Riverside. Wei-Chun will start his new position in January 2024. Congratulations! (12/18/2023)
  • Malek has received a job offer as Clinical Pharmacology Fellow from Center for Computational Biology and Bioinformatics at Indiana University School of Medicine. Congratulations! (12/14/2023)
  • Wei-Chun and Zhoumeng co-presented a webinar entitled “Integrating Machine Learning and Quantitative Structure Activity Relationships (QSAR) Modeling Approaches to Develop Artificial Intelligence (AI)-assited Interactive Physiologically Based Pharmacokinetic (iPBPK) Modeling Web Dashboard”. This webinar was jointly hosted by Risk Assessment Specialty Section (RASS), Biological Modeling Specialty Section (BMSS), and American Association of Chinese in Toxicology (AACT) Special Interest Group of Society of Toxicology. (12/13/2023)
  • Wei-Chun’s review article entitled “Impact of protein coronas on nanoparticle interactions with tissues and targeted delivery” has been accepted by Current Opinion in Biotechnology. Congratulations! (11/22/2023)
  • Our lab did multiple presentations in the Southeastern Society of Toxicology (SESOT) meeting that took place at the University of Georgia, Athens, GA. (11/17/2023)

    2023SESOT

    • Dr. Lin gave a keynote presentation entitled “Integrating machine learning and artificial intelligence with physiologically based pharmacokinetic (PBPK) and quantitative structure-activity relationship (QSAR) modeling to support toxicokinetic and toxicity assessment of xenobiotics”.
    • Qiran gave a platform presentation entitled “A Physiologically Based Pharmacokinetic (PBPK) Model of Perfluorooctane Sulfonate (PFOS) in Adult Zebrafish”.
    • Chi-Yun gave a platform presentation entitled “Development of a physiologically based toxicokinetic model for microplastics and nanoplastics in mice following oral administration with implications for human dietary exposure”.
    • Xue gave a poster presentation entitled “Utilizing Artificial Intelligence based Quantitative Structure-Activity Relationship (AI-QSAR) Models to Predict the Plasma Half-Life of Drugs in Dogs”.
    • Pei-Yu gave a poster presentation entitled “Predicting the Plasma Half-Life of Drugs in Food Animals with Machine Learning and Artificial Intelligence in Quantitative Structure−Activity Relationship Modeling”.
    • Zhicheng gave a platform presentation entitled “Development of a physiologically based pharmacokinetic model for tylosin in laying hens following oral exposure”.
    • Zhicheng also gave a poster presentation entitled “Predicting Multi-Organ Toxicity with a Multi-Task Quantitative Structure–Activity Relationship (QSAR) Model” on behalf of Wei-Chun.
    • Qiran received the Third Place of the Postdoc Platform Presentation Award and Chi-Yun received the Second Place of the Postdoc Platform Presentation Award. Congratulations to the team!
  • Xue is featured by our department during the International Education Week! Check it out here. (11/13/2023)
  • Ethan joins our lab as an Undergraduate Student Researcher. Welcome! (11/13/2023)
  • Kun joins our lab as a Postdoctoral Associate. Welcome! (11/13/2023)
  • Dr. Lin presents a poster entitled “A population pharmacokinetic model with tissue compartments for oxytetracycline in sheep” at the American College of Toxicology (ACT) 44th Annual Meeting. (11/13/2023)
  • Malek presents a poster entitled “Development of a Population Pharmacokinetic Model for Oxytetracycline in Sheep using a Nonlinear Mixed Effects Approach” at the 2023 American Conference on Pharmacometrics (ACoP14). Good job! (11/06/2023)
  • Dr. Lin presents a poster entitled “Development of an artificial intelligence-based PBPK model for nanoparticles in tumor-bearing mice” at the American Association of Pharmaceutical Scientists (AAPS) 2023 PharmSci 360 annual meeting. (10/25/2023)
  • Dr. Lin gives a keynote presentation entitled “Global Health and One Health: Emerging Issues and Future Perspectives on Human, Animal and Environmental Health” at the United Nations Day of UNA*USA Gainesville Chapter. (10/21/2023)
  • Xue presents a poster entitled “An AI-QSAR approach to predict the plasma half-life of drugs in dogs” and Pei-Yu presents a poster entitled “Development of Machine Learning -Based Quantitative Structure−Activity Relationship Modeling to Predict the Plasma Half-life of Drugs in Food Animals” in the 2023 UF AI Days. Good job! (10/18/2023)
  • 2023 UF AI DaysXue’s first manuscript entitled “Pharmacokinetics, Tissue Residue Depletion, and Withdrawal Interval Estimations of Florfenicol in Goats Following Repeated Subcutaneous Administrations” has been accepted by Food and Chemical Toxicology. Well done! (10/11/2023)
  • Wei-Chun’s manuscript entitled “Development and Application of an Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Model for Adult Beef Cattle and Lactating Dairy Cows to Estimate Tissue Distribution and Edible Tissue and Milk Withdrawal Intervals for Per- and Polyfluoroalkyl Substances (PFAS)” has been accepted by Food and Chemical Toxicology. Congratulations! (09/23/2023)
  • Qiran’s manuscript entitled “Meta-Analysis of Nanoparticle Distribution in Tumors and Major Organs in Tumor-Bearing Mice” has been accepted by ACS Nano. Congratulations! (08/24/2023)
  • The UF Component of the Food Animal Residue Avoidance Databank (FARAD) Program has received the 2023 Award. Congratulations to the entire FARAD team! (08/18/2023)
  • Zhicheng joins our lab as a PhD student. Welcome! (08/16/2023)
  • Dr. Lin gives a presentation entitled “Introduction to the history and representative applications of machine learning and artificial intelligence in toxicological sciences” as part of a Session “ChatGPT Is Smart Enough to Pass the MBA and USMLE Tests. . . Is DABT Next” in the 2023 Toxicology Forum Summer Meeting. The co-chairs of this session are Dr. Ivan Rusyn and Dr. Antony Williams. (07/24/2023)Toxicology Forum
  • Wei-Chun’s manuscript entitled “An artificial intelligence-assisted physiologically-based pharmacokinetic model to predict nanoparticle delivery to tumors in mice” has been accepted by Journal of Controlled Release. Congratulations! (07/24/2023)
  • Xue receives the PHHP PhD Fellowship in Artificial Intelligence (AI). Wonderful! Congratulations! (06/30/2023)
  • Dr. Lin gives a webinar presentation entitled “Integration of Machine Learning and Artificial Intelligence with Physiologically Based Pharmacokinetic Modeling and Its Applications in Cancer Nanomedicine, Food Safety, and Chemical Risk Assessment” for US Food and Drug Administration (FDA), Center for Drug Evaluation and Research, Office of Generic Drug, Office of Research and Standards (ORS) Scientific Presentation: Clinical/Data Analytics Track. (06/06/2023)
  • Nithin and Yashas join our lab as OPS Student Research Assistants. Welcome! (05/12/2023)
  • Dr. Lin gives a webinar presentation entitled “Machine learning and artificial intelligence in toxicology and physiologically based pharmacokinetic modeling in supporting chemical and nanoparticle toxicity and dosimetry assessment” for ExxonMobil Biomedical Sciences (EMBSI). (04/26/2023)
  • Qiran receives the EGH Outstanding Postdoc Award. Congratulations! (04/25/2023)
  • Our lab’s PFAS PBPK projects have been featured as part of the Department of Environmental and Global Health’s Research Highlights. Check it out here: https://phhp.ufl.edu/2023/04/13/whats-below-the-surface/ (04/13/2023)
  • Dr. Lin is a co-author of a manuscript entitled “Requirements, Expectations, Challenges & Opportunities Associated with Training the Next Generation of Pharmacometricians” that was just accepted by CPT: Pharmacometrics & Systems Pharmacology. This project was in collaboration with multiple colleagues from Center for Pharmacometrics and Systems Pharmacology (CPSP) and industry and was led by Dr. Stephan Schmidt, Director of CPSP. (04/10/2023)
  • Dr. Chou gives a guest lecture entitled “An introduction to computational modeling and artificial intelligence in exposure science and its application in environmental chemicals, animal drugs, and nanomedicine” for the course “PHC 6702: Environmental Monitoring and Exposure Assessment” at UF. (04/05/2023)
  • Long’s and Qiran’s review article entitled “Pharmacokinetics and tumor delivery of nanoparticles” has been accepted by the Journal of Drug Delivery Science and Technology. Congratulations! (03/30/2023)
  • The Lin lab members did three presentations in the Lake Nona Leadership Council Meeting at the UF Research and Academic Center – Lake Nona on March 28, 2023. Ms. Xue Wu did an “shark tank” style platform presentation entitled “Predicting Withdrawal Times of Flunixin in Cattle Following Dermal Exposure Using a PBPK Model”. Dr. Qiran Chen did a poster presentation entitled “Pharmacostatistical analysis of tissue distribution of nanoparticles in tumor-bearing mice”. Dr. Malek Hussein Hajjawi did a poster presentation entitled “Development of a Population Pharmacokinetic Model for Oxytetracycline in Sheep Using a Nonlinear Mixed Effects Approach”. (03/28/2023)

2023-03-28 Lake Nona

  • Our lab was recognized for leadership, presented several poster and platform presentations, and received several awards at the Society of Toxicology 62nd Annual Meeting held March 19-23 in Nashville. Congratulations to the entire team for another great year! Our lab’s accomplishments have been featured at the college’s website here. The services and awards are listed here. (03/23/2022)
    • Members of the Lin Lab provided the following services:
      • Zhoumeng Lin served as the Chair of the Poster Session on “Computational Toxicology I”. Lin completed his two-year service as the Council for the Nanoscience and Advanced Materials Specialty Section and received the “Outstanding Service as a Councilor Award”. Lin is now in his second year in the Presidential Chain of the Biological Modeling Specialty Section and will start his third year service as the President starting May 1, 2023.
      • Wei-Chun Chou was elected as a Councilor of the Biological Modeling Specialty Section.
      • Qiran Chen served as Chair of the Poster Session on “Computational Toxicology II”. Chen was elected as the Postdoctoral Representative of the Biological Modeling Specialty Section.
    • Members of the Lin Lab received the following awards:
      • Best Publication Award of the Year 2022 presented by Nanoscience and Advanced Materials Specialty Section; Recipients: Wei-Chun Chou and Zhoumeng Lin; Title of the publication “Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats”. Link to the publication: https://doi.org/10.1186/s12989-022-00489-4
      • Outstanding Postdoctoral Award presented by Nanoscience and Advanced Materials Specialty Section; Recipient: Qiran Chen
      • Best Postdoctoral Publication Award presented by Society of Toxicology; Recipient: Qiran Chen
      • Perry J. Gehring Biological Modeling Endowment Award presented by Biological Modeling Specialty Section; Recipient: Xue Wu
      • Best Trainee Abstract Award Honorable Mention presented by Biological Modeling Specialty Section; Recipient: Xue Wu; Title of Xue’s abstract “Development of a Physiologically Based Pharmacokinetic (PBPK) Model for Flunixin in Cattle and Swine Following Dermal Exposure”
  • Dr. Lin gives a guest lecture entitled “Integrating Physiologically Based Pharmacokinetic (PBPK) Modeling with Artificial Intelligence (AI) to Predict Nanoparticle Delivery to Tumors” to students in Department of Pharmaceutical Sciences at St. John’s University. (03/16/2023)
  • Dr. Lin gives a guest lecture entitled “Xenobiotic transport in the body – Physiologically based pharmacokinetic (PBPK) modeling” to the course of “VME 6934: Ecotoxicology and Risk Assessment” at UF. (01/18/2023)
  • Pei-Yu joins our lab as a PhD student in Public Health with a Concentration in Environmental Health. Welcome! (01/03/2023)
  • Dr. Lin gives a presentation entitled “An interactive generic physiologically based pharmacokinetic modeling platform to predict meat and milk residues and withdrawal intervals for perfluorooctanoic acid, perfluorooctane sulfonate and perfluorohexane sulfonate in beef and dairy cattle” at the Annual Meeting of Society for Risk Analysis (SRA) in Tampa. (12/06/2022)
  • Our collaborative manuscript entitled “Integration of In Vitro and In Vivo Models to Predict Cellular and Tissue Dosimetry of Nanomaterials Using Physiologically Based Pharmacokinetic Modeling” has been accepted by ACS Nano. This is great news! Congratulations to the entire team! (12/02/2022)
  • Dr. Jia-Sheng Wang from the University of Georgia visits UF and gives a seminar in our department. Dr. Wang also joins our lab meeting and provides comments on our projects. Thank you! (11/16/2022)

    Dr. Jia-Sheng Wang Visit

  • Malek joins our lab as a Postdoctoral Fellow. Welcome! (10/28/2022)
  • Lin is now certified as European Registered Toxicologist (ERT) through UK Register of Toxicologists. Good news! (11/15/2022)
  • FARAD celebrates its 40th anniversary in Austin. Congratulations to the entire team! (11/08/2022)

    FARAD 2022

  • Wei-Chun’s manuscript entitled “Machine learning and artificial intelligence in physiologically based pharmacokinetic modeling” has been accepted by Toxicological Sciences. Congratulations! (09/22/2022)
  • Xue joins our lab as a PhD student in Public Health with a Concentration in Environmental Health. Welcome! (08/22/2022)
  • Long’s last day with UF. Congratulations again to Long! (08/21/2022)Long Yuan farewell
  • Long is about to complete his two-year postdoc training and has accepted a new position as Senior Scientist in Pharmacometrics in Neurocrine Biosciences, Inc. in San Diego, CA. In the last two years, Long received training in various pharmacometrics methods, including traditional PK and PBPK modeling. Long has published two first-authored papers, and has a couple of more papers that are in preparation. Long has also received several national and regional awards, including the Andersen-Clewell Trainee Award presented jointly by the Risk Assessment Specialty Section and Biological Modeling Specialty Section of Society of Toxicology in 2022 and the John Doull Risk Assessment Award presented by Risk Assessment Specialty Section of Society of Toxicology in 2021. Congratulations to Long and thanks to his contributions to the lab! (08/05/2022)
  • The UF Component of the Food Animal Residue Avoidance Databank (FARAD) Program has received the 2022 Award. Congratulations to the entire FARAD team! (08/04/2022)
  • Long’s manuscript entitled “A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in broiler chickens and laying hens” has been accepted by Food and Chemical Toxicology. Congratulations to the entire collaborative team! (07/25/2022)
  • Our lab’s article entitled “Machine learning and artificial intelligence in toxicological sciences” has been accepted for publication in Toxicological Sciences. Great news! (07/02/2022)
  • Wei-Chun’s manuscript entitled “Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats” has been accepted by Particle and Fibre Toxicology. Congratulations! (06/28/2022)
  • Our lab’s Nano AI PBPK work is featured in the main page of our department website here. Congratulation to the entire lab! (06/07/2022)
  • Zhoumeng and Wei-Chun present our work for a webinar hosted jointly by National Health Research Institutes and National Yang Ming Chiao Tung University of Taiwan. The title of Zhoumeng’s talk is “Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling in Nanomedicine and Food Safety Assessment and Roles of Artificial Intelligence (AI) Approaches in these Areas”. The title of Wei-Chun’s talk is “Development of Physiologically Based Pharmacokinetic (PBPK) Models Within Bayesian Framework and roles of artificial intelligence technologies in human health risk assessment: a case study with perfluorooctane sulfonate (PFOS)”. (05/18/2022)
  • Wei-Chun’s paper entitled “An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol and Penicillin G” has been accepted by Toxicological Sciences. Congratulations! (05/20/2022)
  • Long’s paper entitled “Residue depletion profiles and withdrawal interval estimations of meloxicam in eggs and ovarian follicles following intravenous (Meloxicam Solution for Injection) and oral (Meloxidyl®) administration in domestic chickens (Gallus domesticus)” has been accepted by Regulatory Toxicology and Pharmacology. Congratulations! (04/15/2022)
  • Qiran’s paper entitled “Toxicokinetics, dose-response and risk assessment of nanomaterials: methodology, challenges, and future perspectives” has been accepted by WIREs Nanomedicine & Nanobiotechnology. Congratulations! (04/12/2022)
  • Gabriel’s paper entitled “Development of a physiologically based pharmacokinetic model to predict irinotecan disposition during inflammation” has been accepted by Chemico-Biological Interactions. Congratulations! (04/11/2022)
  • As usual, our lab presents multiple posters and platform presentations and receive several awards at the Annual Meeting of Society of Toxicology. Congratulations to the entire team for another great year! Our lab’s accomplishments have been featured at the college’s website here. The awards are listed here. Please refer to the SOT Program for details of our presentations. (03/22/2022)
  • Ning’s manuscript entitled “Comparative pharmacokinetics of sulfadiazine and its metabolite N4-acetyl sulfadiazine in grass carp (Ctenopharyngodon idella) at different temperatures after oral administration” has been accepted by Pharmaceutics. Congratulations! (03/22/2020)
  • Congratulations to Gabriel on his new position as a Senior Scientist in the ADME & Discovery Group at Merch in Boston, MA. Gabriel will start this new position in March. We are very proud of you. (02/25/2022)
  • Qiran’s manuscript entitled “Integration of Toxicogenomics and Physiologically Based Pharmacokinetic (PBPK) Modeling in Human Health Risk Assessment of Perfluorooctane Sulfonate (PFOS)” has been accepted by Environmental Science & Technology. Congratulations! (02/11/2022)
  • Qiran, Wei-Chun, and Long receive the Postdoctoral Fellow Poster Awards of the 2021 Annual Meeting of Southeastern Society of Toxicology (SESOT). Congratulations to all! (12/20/2021)
    • Qiran’s poster title is “The Implementation of Toxiocogenomics and Physiologically Based Pharmacokinetic (PBPK) modeling to the Human Health Risk Assessment of Perfluorooctane Sulfonate (PFOS)”.
    • Wei-Chun’s poster title is “A web-based platform based on a generic physiologically based pharmacokinetic (PBPK) model to predict withdrawal intervals of flunixin, florfenicol, and penicillin G in cattle and swine”.
    • Long’s poster title is “A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in domestic chickens”.
  • Dr. Lin delivers a webinar entitled “Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling in Nanomedicine, Food Safety and Human Health Risk Assessment and Roles of Artificial Intelligence (AI) Approaches in these Areas”. This is part of the webinar series hosted by ScitoVation, Durham, NC. The recording is available here. (12/07/2021)
  • Dr. Lin is named in the World’s Top 2% Scientists List in 2020 published by Stanford University. Here is the full citation information of this list. “Baas, Jeroen; Boyack, Kevin; Ioannidis, John P.A. (2021), “August 2021 data-update for “Updated science-wide author databases of standardized citation indicators””, Mendeley Data, V3, doi: 10.17632/btchxktzyw.3”. (11/22/2021)
  • Riad’s last day with UF. Congratulations again to Riad! (10/29/2021)Riad Lab Photo
  • Our lab receives a new subcontract from The Children’s Hospital of Philadelphia (CHOP). The objective of this subcontract is to identify efficient sampling interval to effectively construct time-concentration profile of bisphenol A in the infant’s urine using a PBPK model. This new subcontract becomes part of the existing subcontract between CHOP and UF that is led by the PI Dr. Eric Coker. Dr. Lin is Co-PI of this subcontract. (10/06/2021)
  • Our lab’s R01 grant is featured on PHHP website. Check it out here. This news has also been picked up by Nano Magazine and NanoWerk. (09/30/2021).
  • Dr. Lin gives a seminar entitled “Application of Pharmacometrics in Veterinary Medicine and Translation of Pharmacokinetics/Pharmacodynamics from Animals to Humans” as part of the EGH seminar series. A recorded presentation is available upon request. (09/30/2021)
  • Riad has accepted a new position as Senior Quantitative Systems Pharmacologist 1 in AbbVie in North Chicago, IL. Riad completed his postdoc training within only a little bit more than one year. During this time, he received the Andersen-Clewell Trainee Award of Biological Modeling Specialty Section and Risk Assessment Specialty Section of Society of Toxicology, and he published one manuscript in Toxicological Sciences. He also completed the manuscript draft of his second major project and had great progress on his third project. Congratulations to Riad and thanks to his contributions to the lab! (09/27/2021)
  • Our lab receives a new subaward to develop a PBPK model for PFOS in daily cows from University of California-Davis. (09/10/2021)
  • Our lab receives our first R01 grant from NIH. This grant is based on extensive foundational work from our lab in the last several years. Thanks to the contributions from prior and current lab members and collaborators. Congratulations to all! (09/01/2021)NIBIB
  • Gabriel has completed his training at UF and returned back to his home university. This summer, Gabriel learned PBPK modeling and developed a PBPK model for irinotecan in mice and humans as part of his PhD dissertation. (08/22/2021)
  • Dr. Lin has completed the UF First Year Faculty Teaching Academy (FYFTA) program. This is part of the preparation to develop and teach new courses at UF beginning in 2022. (08/04/2021)
  • Riad’s manuscript entitled “Development and Application of an interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats” has been accepted by Toxicological Sciences. Congratulations! (07/27/2021)
  • The UF Component of the Food Animal Residue Avoidance Databank (FARAD) Program has received the 2021 Award. Congratulations to the entire FARAD team! (07/20/2021)
  • Gabriel has joined our lab as a Visiting PhD Student. Welcome! (07/12/2021)
  • Dr. Lin and all his lab members have moved to the University of Florida. (05/28/2021)

Click here for news archives from 2016 to 2021 at K-State.